Dallas, Tarrant, Denton and Collin County health departments will have limited amounts of flu vaccine when they reopen on Monday morning.
Patients are flooding emergency rooms across the country. The flu has hit 41 states including Texas and the season is just getting started.
Shortages of flu vaccine are being reported in some parts of North Texas.
Because of a spike in flu cases, some area pharmacies also have run out of Tamiflu, the virus-fighting prescription medication.
The best advice for medicine or vaccine is to call in advance to find out who has what you need.