Mayo and Kaman scored 17 of Dallas' last 19 points to help the Mavericks win their seventh straight at home against the 76ers.
Dorell Wright scored 25 points and Spencer Hawes had 18 for the 76ers, who lost their fourth straight game. Philadelphia point guard Jrue Holiday, the team's leading scorer at nearly 19 points per game, missed his third straight game with a sprained left foot.
Dallas point guard Derek Fisher left the game with 6:50 left in the first quarter with a strained right knee and did not return. Fisher, who wasn't expected to play because of the flu, went down to the ground after having his shot blocked by Evan Turner. The 17th-year guard walked slowly to the locker room.